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The protein p53 encoded by this gene inhibits the development of tumors through the regulation of the cell cycle, apoptosis, genomic stability and other pathways

Continuous variables are presented as the mean standard error of the mean (s.e.m.)

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Ethyl Pyruvate Decreases HMGB1 Release and Ameliorates Murine Colitis

doi: 10.3389/fphar.2022.1089130 Received 03 November 2022 Accepted 07 December 2022 Published 19 December 2022 Volume 13 - 2022 Edited by Xin Wang, Hokkaido University, Japan Reviewed by Jesus Osada, University of Zaragoza, Spain Dharmani Devi Murugan, University of Malaya, Malaysia Updates Copyright 2022 Garca-Berumen, Vargas-Vargas, Ortiz-Avila, PiaZentella, Ramos-Gmez, FigueroaGarca, Meja-Zepeda, RodrguezOrozco, SaavedraMolina and Corts-Rojo

These attributes collectively enhance the therapeutic performance by minimizing off-target exposure and systemic toxicity (22)