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For example, propionyl-l-carnitine, but not l-carnitine or propionate, is therapeutic to intestinal pathology in ulcerative colitis (217)

A study in germ-free mice versus mice colonized with gut microbiota showed that the gut microbiota influences the hosts development of hypertensive organ damage, with TMAO and other microbial metabolites such as short-chain fatty acids (SCFAs) contributing to the phenotype (Avery et al., 2023)