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Next, participation of lipid peroxidation, NCOA4-mediated ferritinophagy, and ferroptosis was examined using human lung samples

doi: 10.1016/j.ejphar.2008.06.016 62 PradeepK.ParkS

Once inside the cell, one of the 2 Cl groups is replaced by water producing a reactive nucleophilic species that enters the nucleus where it can covalently modify DNA (primarily by intrastrand binding to adjacent guanines) and cause cell death

Recessive variants in ZNF142 cause a complex neurodevelopmental disorder with intellectual disability, speech impairment, seizures, and dystonia

Many cancer cells which rely on glutamine catabolism for building blocks and energy have been reported to be addicted to glutamine [33,82-84]

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