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This damage may include: pulmonary edema, which is a buildup of fluid in the lungs cardiac ischemia, which happens when the blood flow to the heart becomes reduced acute kidney failure neurological dysfunction, which refers to a disorder of the central nervous system eclampsia, which is when high blood pressure leads to seizures during pregnancy aortic dissection, which happens when a tear develops in the aorta A numbness or weakness on one side of the body aphasia, which is when a person has difficulties with speech and language blurry vision ataxia, which is a group of disorders that affect a persons balance, coordination, and speech Treatment Medical professionals will aim to lower a persons blood pressure rapidly

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Reference ranges vary slightly between laboratories, but the general framework used by most U.S

In preclinical heart failure models, NNMT enzyme inhibition markedly reduced cardiac 1-MNA (by 77.1%), improved cardiac function, reduced left ventricular hypertrophy and fibrosis, and decreased pro-inflammatory gene expression

Informed Consent For this type of study informed consent is not required

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