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Furthermore, the levels of GSH decreased with increased oxidative stress markers in the HFD-fed mice, which reflect the exhaustion of antioxidant potential and increased oxidative stress

A 50 kDa His 6 -tagged protein was adequately expressed in E

Furthermore, the mice respond to the different treatments with NASH resolution (OCA & semaglutide, not with cenicriviroc) and improvement with fibrosis (OCA only), in line with clinical trials

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Importantly, as illustrated in graphical abstract, TF inhibits multiple pathogenic mechanisms triggered not only by iron but also by lipid peroxidation in iRPE cells, suggesting that TF is a promising therapeutic option for protecting cells from damage associated with GA

To view a copy of this licence, visit About this article Cite this article Liao, Y., Shi, Y., Zeng, S