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Somatic mutation analyses of the tumour derived from an LS affected family member, revealed a high mutational burden (959 mutations) in a clinical exome panel

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Foster AC, Jacques BE, Piu F

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An alternative approach is the de novo synthesis of compounds, which offers several advantages, including rapid proliferation, year-round metabolite production independent of environmental conditions, and sometimes the metabolite content is higher compared to the mother plant 5,6

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