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The beneficial effects of EGCG on photoaged skin primarily include improvements in elasticity, enhanced moisturization, inhibition of damage, and reduction in pigmentation

GCH1 catalyzes the conversion of GTP to formic acid and dihydroneopterin triphosphate, the initial and rate-limiting step in BH4 synthesis (180,181)

Yagihashi S, Mizukami H, Sugimoto K (2011) Mechanism of diabetic neuropathy: where are we now and where to go

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Both intramuscular and intragastric administration significantly reduce ulcer area and accelerate healing across different experimental models

To comprehensively determine the cellular components of the tumor microenvironment across different stages of pancreatic cancer, we used the CIBERSORT in silico cytometry method (Newman et al., 2015) to evaluate 22 different immune cell types in 36 normal tissues and 36 tumor tissues in GSE15471, and 153 tumor tissues at different stages in TCGA