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Its not replacing nicotine its maintaining nicotine, he says

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They mainly viewed e-cigarettes as a smoking cessation aid to help them eventually quit nicotine altogether: I think some people see it as more like a hobby, its like, now Im not smoking Im going to vape, but I see it more like cutting down, using it to quit, and then I want to get rid it, and then only use it if I need it for social occasions (F22) In contrast to the other groups, many of those who wanted to quit e-cigarettes wanted to because they were uncomfortable having a dependency: I dont like the idea of being addicted to anything

The length of time before surgery you abstain from smoking can make a huge difference to the outcome

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Another study published that year in the International Journal of Molecular Sciences , researchers at the University of California, San Diego, found that giving nicotine to mice with Parkinsons disease decreased the motor problems that are characteristic of the neurodegenerative condition