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Lipogenesis inhibition means fewer new fat deposits are forming

It does not prove that human appetite would remain unchanged or that a human body-composition effect would occur

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Its short half-life potentially reduces some systemic risks, but short-term trials werent revealing of weight results

When You Might Need Folic Acid or B12 Supplements Dietary insufficiency is a common reason for supplementation

In adipose tissue (where NNMT is highly expressed), inhibition activates the polyamine flux pathway and shifts adipocytes toward a 'beige' phenotype with elevated energy expenditure