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Mitochondrial dysfunction itself can be categorized into two types: the first type represents a mutation of a gene which is associated with the ATP-generating pathway, while the second one is related to various abnormalities such as genetic, biochemic or metabolic, that may weaken the ability of the mitochondria to produce ATP (Haas et al., 2007)

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The presence of SVCT2 has been primarily described in the adult cerebellum (Oyarce et al., 2018)

Complementing it with B-complex vitamins is absolutely a necessity

To summarise, ageing is accompanied by significant decline in astrocytic haemostatic and neuroprotective capacities, which may directly affect nervous tissue and increase it vulnerability to pathological attacks and neurodegeneration