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Glutathione is a potent antioxidant which acts to prevent damage to important cellular components caused by reactive oxygen species such as free radicals and peroxided

doi: 10.1038/s41576-018-0018-x 121 ToupsK.HathawayA.GordonD.ChungH.RajiC.BoydA.et al

The present study addressed this knowledge gap and demonstrated that CUR alleviates AFB 1 -induced damage to the gut-kidney axis in sheep through multiple pathways: it inhibits the activity of the ATF6/GRP78 signaling pathway and the NF-B signaling pathway, upregulates NRF2/KEAP1 signaling pathway, activates the antioxidant system, and reduces AFB 1 -induced injury to the intestines and kidneys of sheep

Front Biosci 28:198