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Additionally, NRC-03 and NRC-07, two AMPs from the pleurocidins AMP family, exhibited equal killing effect at a concentration of 50M on normal MCF7 cells and on paclitaxel-resistant breast cancer cell line MCF7-TX400 that possess 2.6 times of P-gp expression more than the normal MCF7 cells, achieving about 60% of cell killing rate

CSC in HNSCC were inhibited with PF-2341066 (a c-MET inhibitor) and -Catenin was shown to be the downregulating factor contributing to CSC elimination [92]

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10.1007/s12035-025-04703-0 61 LiY.JiangJ.LiJ.LiuS.WangC.YuZ.et al (2025b)