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The mTBI model in this study has been characterized to deliver repetitive, biomechanically relevant impacts, to induce CTE-like neuropathology and cognitive impairment ( TDP-43 is an important protein for stabilization of RNA processes such as transcription, mRNA stability and alternative splicing ( A key constituent of these NFTs is tau, a microtubule-associated protein involved in axon construction (Yin et al., 2010), but the tau-mediating involvement of ALC in mTBI has not been previously demonstrated

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21, 22 Further, ROS production has been demonstrated to occur not only in the endothelial cell layer but also within the media and adventitia, all of which may impair NO signaling within vascular tissues

Procesul patentat de obinere natural a lipozomilor a luat natere dintr-un studiu atent al structurilor lipidice i dezvoltarea, n parcursul mai multor ani, de diferite metode de nfurare a lipidelor n jurul unor enzime i molecule, astfel nct aceastea s poat fi studiate n mediul lor natural cu scopul obinerii de rezultate exacte

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Front Mol Neurosci 10:451 Ziemens D, Oschmann F, Gerkau NJ, Rose CR (2019) Heterogeneity of activity-induced sodium transients between astrocytes of the mouse hippocampus and neocortex: mechanisms and consequences