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275,276 SGLT-2Is reduce MACE (primarily by reducing cardiovascular death), 277 hospitalizations due to heart failure, 278 and CKD progression 278 (including significant reductions in albuminuria and delayed eGFR decline) in various populations, irrespective of baseline glycemic status

Marnewick, J.L., Van Der Westhuizen, F.H., Joubert, E., Swanevelder, S., Swart, P., Gelderblom, W.C.A

The critical role of glucuronidase treatment has also been emphasized by Ali et al

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Shkolnik K, Tadmor A, Ben-Dor S, Nevo N, Galiani D, Dekel N: Reactive oxygen species are indispensable in ovulation

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