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Further studies revealed that PF was able to increase tolerance to stressors in rats by modulating the hyperactive HPA axis, exerting antidepressant effects similar to those of fluoxetine, as evidenced by the significant reduction of corticotropin-releasing hormone (CRH), ACTH, and CORT in plasma and hippocampus (Yan-xia et al., 2014)

Acta Chem Scand 47:138144

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Participants were recruited through the South London Stroke Register (SLSR) and from national stroke charities

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Thambo, J.-B