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In the case of PT-141, a growing body of research and case data supports its safety and effectiveness in male patients, especially those for whom PDE5 inhibitors have failed

PT-141, also known as Bremelanotide, became the first FDA-approved treatment specifically targeting hypoactive sexual desire disorder in women, validating decades of research into melanocortin-based sexual function modulation

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The study did not enroll patients with BRAF V600 pathogenic variants with high LDH levels and symptomatic or rapidly progressive disease who had not received anti- BRAF therapy, which could provide rapid clinical benefit