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These findings demonstrate that overexpression of GSTA4 promotes CRC cell proliferation, tumorigenesis, and chemoresistance, indicating that GST A4 blockade may lead to clinical benefits in CRC therapy

The math is surprisingly simple once you understand the variables

We studied the impact of alcohol consumption on liver-related parameters in individuals with the characteristic heterozygous/homozygous Pi*Z variant (Pi*MZ/Pi*ZZ genotype) found in the community-based United Kingdom Biobank (UKB) and the European Alpha1 liver consortium