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Similar increases in glutathione tissue levels were attained by Meister by administering an alkyl monoester of glutathione (U.S

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J Clin Invest 128:2635

[Abstract] Trametinib, a MEK1/2 inhibitor, strongly inhibits growth and partially reverses GW786034 resistance of GW786034-resistant clones.Trametinib-induced inhibition of phosphorylation of ERK1/2 in SS clones is assessed by Western blot analysis with anti-ERK1/2 and anti-phospho-ERK1/2 antibodies