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Both parameters were affected stronger by RNAi administered earlier in life, presumably reflecting the longer exposure to the dsRNA-producing bacteria and the higher rate of their ingestion early in adulthood 35 (Fig

Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28

Quantified fluorescence intensity measurements are shown in Fig

Based on overall rates of missense variation [71, 72], we might expect every individual to carry roughly 510 missense alleles in these enzymes on average