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Several studies have shown that the XPC rs2228001 (Lys939Gln) polymorphism is significantly associated with bladder cancer risk, particularly in individuals with occupational exposure to chemical carcinogens (Dou et al., 2013

This is a type of post-translational modification known as S-glutathionylation, which protects proteins from irreversible oxidation, but can disrupt their function

[DOI] [PubMed] [Google Scholar] 47.Sinicrope F.A

Electrochimica acta 46 , 24992505, (2001)

Additionally, by inhibiting the hyperphosphorylation of c-Jun N-terminal kinase, curcumin prevents the mitochondrial translocation of the pro-apoptotic factor Bax, subsequently reducing dopaminergic neuronal death and striatal axonal degeneration (Pan et al., 2012)

Rizzollo, F., More, S., Vangheluwe, P