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DNA Synthesis Vitamin B12 is essential for DNA synthesis

the MHRA advises checking vitamin B12 levels if deficiency is suspected and considering periodic monitoring in those with risk factors [6] Chronic alcohol consumption can damage the gastric mucosa and impair absorption Nitrous oxide exposure (including recreational use) can inactivate vitamin B12 in the body, causing functional deficiency and neurological symptoms If you experience symptoms such as unexplained fatigue, pale skin, shortness of breath, neurological symptoms (tingling, numbness, balance problems), mood changes, or cognitive difficulties, contact your GP promptly

Those most commonly affected include people over 50 as the ability to absorb B12 from food naturally declines with age as well as vegetarians and vegans, those with pernicious anaemia, anyone who has undergone gastrointestinal surgery, and those living with digestive conditions such as Crohn's disease or coeliac disease

B12 plays a direct role in nerve function and cognitive health

recommends that you take a daily B12 supplement providing at least 50 micrograms per day, or one weekly supplement providing 2,000 micrograms