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RNA interference (RNAi) and antisense oligonucleotides (ASOs) enable selective silencing of maladaptive genes, such as those driving lipid metabolism dysregulation (silencing ACSL4 or activating GPX4 expression), inflammation, or myocardial remodeling

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Lipid peroxidation Lipid peroxidation after exposure to H 2 O 2 was assessed using the oxidation-sensitive lipid peroxidation probe Bodipy-C11 (#D3861, Invitrogen) [25]

11.6 Diversification of probiotic sources and delivery vehicles Regarding delivery matrices, the future sources of probiotics are expected to diversify beyond traditional fermented dairy, cereals, fruits, and vegetables to encompass novel vehicles such as meat, fish, honey, and even environmental origins like soil (536)