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10.1074/jbc.m602979200 J

Wu, J.X

Cells then recycle it back using an enzyme (glutathione reductase), creating a powerful protection cycle

Integrative Comparative Physiology 325 (6), R665R681

Spectral and EPR studies have revealed the presence of a trihydrobiopterin (BH 3 ) radical intermediate, which strongly supports a redox role for BH4 in NOS catalysis and may explain the ability of eNOS-bound BH4 to limit the release of oxygen as O 2 [39]