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The reduced infiltration of inflammatory cells into perivascular and connective tissues was also demonstrated in another study with apigenin treatment (5 mg/kg, 10 mg/kg) (Fig

Background fluorescence was determined in each individual experiment with cells exposed to Triton (1%) and subtracted from all other values

In rodent models, it has been reported to protect against various gastrointestinal insultsulcers, NSAIDinduced lesions, ischemia/reperfusion injuryby promoting angiogenesis, upregulating growth factors, and modulating nitric oxide pathways