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For example, Nrf2, a representative antioxidant gene, activates the transcription of ferritin heavy chain 1 (a protein involved in iron storage) and heme oxygenase-1 (a protein involved in heme breakdown) to reduce labile iron and regulate iron metabolism and oxidative stress [15,45]

Levels increased by about 40% in whole blood, 25% in red blood cells, 28% in plasma, and 100% in immune cells

Phytomedicine 7 (1), 713

S2CID 13352894

Numerous reports have shown in both in vitro and in vivo cancer studies that conjugation of drugs to a triphenylphosphonium (TPP + ) moiety linked through an alkyl side chain selectively target mitochondria of cancer cells more so than normal cells 18,19

For instance, AuNPs could be functionalized with drugs or targeting molecules and used for targeted delivery of drugs or as contrast agents for imaging