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Geuna, E

J Neurochem 2008

With regard to NF-B signaling, bortezomib, the first FDA-approved proteasome inhibitor for multiple myeloma, exerts part of its antineoplastic effects through a pharmacological mechanism that targets the NF-B signaling pathway

Pulipati S, Puttagunta SB, S KV, et al

The cell division cycle-dissociated protein 4 (CDCA4) knock-down by RNA interference in MCF-7 human breast cancer cell lines resistant to Adriamycin (MCF-7/ADM) decreased the percentage of cancer cells by 50%