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In some formulations developed for administration to a mammal, and for formulations formulated for human administration, the auris-acceptable gel comprises substantially all of the weight of the formulation

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In some embodiments, the amount of thermoreversible polymer (e.g., pluronic F127) in any formulation described herein is about 12% of the total weight of the formulation

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[2] See, e.g ., FDA, Warning Letter to Expert Aesthetics (Sep

Subjects with refractive errors that could not be corrected with eyeglasses or routine contact lenses, and those who were scleral or mini-scleral contact lens intolerant were included