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Glutathione may help support the body's response to these reactions, thereby promoting cellular protection

Proc Natl Acad Sci 84:439443 Gutirrez J-C, de Francisco P, Amaro F et al (2019) Structural and functional diversity of microbial metallothionein genes

No other funding or sponsorship has been received for this work

High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission

In lung adenocarcinoma (LUAD), PDK1 is markedly upregulated and promotes cisplatin resistance by enhancing the DNA damage response through the E2F8/PDK1 axis [134]