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These observations raise the possibility that UBQLN2 is a common catalyst for multiple aggregation-prone proteins, providing a mechanistic link to the frequent co-occurrence of -syn and tau pathologies in PD (Cisbani et al, 2017

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Some clinical studies have documented reductions in high-sensitivity C-reactive protein (hsCRP) among patients treated with tirzepatide for type 2 diabetes or obesity

Niki E, Noguchi N, Tsuchihashi H, Gotoh N

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10.1016/j.neuroimage.2011.10.090 122 Ivimey-CookE

Doxycycline-inducible cyclin D replacement system and cell line construction The pINDUCER system was used to generate doxycycline-inducible CCND1 shRNA and shRNA-resistant CCND1 RPE-1 cells 60