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Life 13 , 1786 (2023)

Function 2 , zqab028 (2021)

Moreover, distinct cytokine signatures have been associated with varying severity levels of ME/CFS, where higher levels of plasma pro-inflammatory cytokines, such as colony-stimulating factor 2 (CSF2), correlate with increased physical and fatigue symptoms in these patients (Giloteaux et al., 2023)

Accumulating evidence would also suggest that insufficient IGF-I levels play a role in vascular diseases such as atherosclerosis and restenosis[155], what will be discussed in further sections (cardiovascular diseases)