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10.1016/j.bbamcr.2008.10.002 Biochim

2 Cys (either within the same protein or between 2 proteins) can link together (protein)-SH + HS-(protein) (protein)-S-S-(protein) to give you a DISULFIDE BOND or cross-link between 2 Cys residues in the same or different proteins -SH + -SH -S-S- More on what these terms mean in a sec, but the key take-away is that, unlike other charm-charm interactions, which are just *attractions* based on charge (or partial charge) differences, this is a covalent bond, so its strong (and good for sturdying-up secreted proteins that have to live outside the comfort of the cell)

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10.2337/dc20-3133 24 LiD.GouJ.ZhuJ.ZhangT.LiuF.ZhangD.et al (2023)

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