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Both are dominated by gastrointestinal adverse events nausea, constipation, diarrhea, vomiting that are mostly mild-to-moderate and dose-related

What Is Tirzepatide

Both reduce appetite and slow gastric emptying, but through different receptor systems

Tirzepatide is a first-in-class dual incretin receptor agonist a single molecule that activates both the GIP (glucose-dependent insulinotropic polypeptide) and the GLP-1 (glucagon-like peptide-1) receptors, which is why it is often nicknamed a twincretin. [7] By engaging two incretin pathways it enhances glucose-dependent insulin secretion, promotes satiety, and delays gastric emptying, producing large effects on both glycemic control and bodyweight

Amylin vs

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