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517 However, PERK heterozygous deficiency exacerbates IFN-induced apoptosis of remyelinating oligodendrocytes and impairs remyelination in cuprizone-induced demyelinated lesions

however, geographical location and ethnicity influence the prevalence of certain symptoms Individual factors such as personal history, current health status (particularly obesity) and socioeconomic status considerably worsen a woman's experience of menopause Health-care providers should offer education to women on improving modifiable lifestyle factors to reduce the risk of future illness Menopause seems to accelerate the ageing process

Pekna has been supported by grants from Swedish Research Council (2024-02814), the Swedish state under the agreement between the Swedish government and the county councils, the ALF agreement (1005387), The Swedish Brain Foundation (FO2023-0157) and The Swedish Stroke Foundation

J Biol Sci 9:4450

Li H, Zhu H, Xu CJ, Yuan J (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

Gherardi E, Birchmeier W, Birchmeier C, Vande Woude G