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Nature communications 11(1), 2020

While early studies centred on cases obtained from institutionalised psychiatric settings [92, 93, 98], cases were later recruited through internal research registers [64], multiple centres [47, 50, 64, 70, 71, 88, 95, 96] or community advertisements [75]

NAD functions as a coenzyme that cells need to produce energy and repair DNA

The abundance of Shigella and Aspergillus species and fecal BAs levels in the rat intestine were significantly reduced by MLB intervention, suggesting that MLB may restore the integrity of the intestinal barrier and inhibit the release of BA-induced inflammatory cells through localized modulation of the gut microbiota and BA metabolism, slowing renal injury (224)

It indicates that the non-GSH-dependent cysteine metabolism involves in the regulation of ferroptosis and also plays an important role in affecting the vulnerability of cells towards ferroptosis