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Nevertheless, vitamin K and its derivatives and analogues might be useful in asthma [75], as their administration has ameliorated the asthma outcomes in 90% of mild, 86% of moderate, and 72% of severe adult asthmatics after one year of treatment [76]

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The affected limb may need to be amputated if these skin ulcers do not heal, or become larger, deeper, or infected

It is important to consult with your GP to confirm that you are suitable for the treatment