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Using 18F-fluorodeoxyglucose positron emission tomography, researchers have detected significantly elevated glucose metabolism in human atherosclerotic plaques, particularly within lipid-rich necrotic cores and regions densely infiltrated by immune cell ( In addition to immune cells, vascular non-immune cells, such as endothelial cells and smooth muscle cells (SMCs), also participate in trained immunity during atherosclerosis

Majtan, T., Kozich, V

In view of the socioeconomic and lifestyle factors associated with UPF consumption, greater consideration should be given to multidisciplinary-based interventions when managing patients across a broad range of clinical settings, particularly as limited access to whole foods and constraints on cooking ability may be significant barriers to patients implementing appropriate dietary changes

10.1111/j.1752-8062.2009.00095.x

The brain is a metabolic organ of high energy demands but does not have much energy reserve

Castelo-Branco C, Soveral I