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In their family-based study, relatives of people with BP-II had a higher risk of also having BP-II, suggesting it tends to run specifically in families (Heun and Maier, 1993)

Given that we only have access to the nominator's summary of their internal data to observe changes in usage trends, which may not be generalizable, we proposed to maintain the current direct PE supply and equipment inputs for CPT code 95800

Since the payment methodology for the new add-on code for Opvee (G0532), the weekly bundled payment for weekly Brixadi (G0533), and the update to the monthly bundled payment for injectable buprenorphine (HCPCS code G2069) is based on comparable and existing drugs billed under the Medicare OTP benefit, and assuming an OTP may provide these new drugs to a Medicare beneficiary in lieu of the comparable and existing drugs under the Medicare OTP benefit (e.g, Opvee instead of Narcan or Kloxxado, or the weekly or monthly formulation of Brixadi instead of Sublocade), then CMS estimates the financial impacts of these new drugs would be negligible

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