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Am J Hum Genet 63:13521362

Although its exact etiology has not yet been fully elucidated, it is accepted that the onset of UC occurs due to an inappropriate aggressive inflammatory response

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Transition metal ions stimulate lipid peroxidation both through the Fenton reaction and by breaking down lipid hydroperoxides into more reactive peroxyl and alkoxyl radicals

Baseline testing of malondialdehyde (MDA), glutathione peroxidase (GPx), and glutathione reductase (GR) activity, alongside TPO antibodies and TSH, helps your provider assess whether oxidative stress is a meaningful contributor to your thyroid dysfunction and whether supplementation is justified

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