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Similarly, an analysis of data from over 400,000 participants in the UK Biobank uncovered that machine learning-based pipelines outperformed the Framingham risk score and Cox proportional hazards model in predicting CVD risk (94)

In agreement, TRPC1/3 knockouts (Molnr et al., 2016) and specific pharmacological blockers of TRPC promote a marked decrease in intracellular Ca 2+ currents in Mller cells, supporting the hypothesis that SOCE is a TRPC channel (Molnr et al., 2016

Eur J Pharmacol 892:173689

Knut Woltjen for sharing plasmids via Addegene

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