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HFD was initially employed to cause insulin resistance, followed by the administration of a low dose of STZ to selectively destroy pancreatic -cells, which are the primary source of insulin within the islets of Langerhans

Differential cytotoxic activity of Quercetin on colonic cancer cells depends on ROS generation through COX-2 expression

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Sun Y-S, Zhao Z, Yang Z-N, Xu F, Lu H-J, Zhu Z-Y, et al

(2) the high electron density of the Ru centers optimizes the binding strength of oxygen species and enhances the resistance to H 2 O 2 toxicity for Ru-hydroxide