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Oxidation and nitrosylation of cysteines proximal to the intermediate filament (IF)-binding site of plectin: effects on structure and vimentin binding and involvement in IF collapse

While promoting tissue homeostasis, lactate functions as both an immunosuppressant and a pro-carcinogen (16)

Chromatographic separation of polar and semi-polar metabolites was performed on a high-resolution reversed-phase C18 column (100 2.1 mm, 1.81.9 m particle size) maintained at 40 C, which provides high peak capacity and reproducibility for complex metabolite mixtures, following the procedure reported by Wei et al

Izzo LT, Wellen KE

In addition to being able to impair the antigen presentation capacity of DCs (164166), these immunosuppressive molecules can also inhibit the activity of T cells and induce the differentiation of T cells into Tregs (141, 167)

Yan, Y., Wang, W., Wu, M., Jetten, M