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GPx4 is widely recognized as the gatekeeper for ferroptosis, which utilizes GSH to selectively detoxify lipid peroxides [12]

doi: 10.1210/en.2015-1896 165 FujimotoN

therefore, TLR4 knockout ( tlr4 / ) mice were used to determine whether resistin induces hypertension and IR through TLR4

Although the clinical significance of these effects is still being explored, they suggest that fosfomycin may confer dual benefits by modulating host immune and inflammatory responses

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Although fermentation and the enzymatic approach provide promising results, they may pose some inherent risks due to the formation of new epitopes