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TGF- attracts BM-MSCs to the sites of bone remodeling, where IGF-1/IGF-1R signaling induces osteoblast differentiation of cells through the PI3K/AKT/mTOR pathway, which preserves bone mass and skeletal microarchitecture

Bioorg Med Chem (2016) 24(21):5088102

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Baobab seed oil also brings some Vitamin E that provides mild antioxidant activity and helps keep the oil itself stable

10.1038/s41581-024-00820-6 52 FriedlanderM

Physical agitation shaking the vial introduces mechanical stress that disrupts tertiary structure in larger peptides