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10.2741/4525 325 StorzP.DpplerH.TokerA

Conditions that predispose to accumulation of excess iron can be hereditary (e.g., hemochromatosis) or acquired (e.g., excess iron ingestion, chronic liver disease)

doi: 10.1146/annurev-physiol-021014-071931 74 KobayashiKSalathMPrattMMCartagenaNJSoloniFSeyboldZVet al

Among these, inflammatory conditions, such as IBD, and functional bowel disorders, such as IBS, are both characterized by a well-established microbiota dysbiosis associated with impairment of intestinal permeability