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Hong X, Miao K, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Pang Z, et al

Piperlongumine targets NF-B and its downstream signaling pathways to suppress tumor growth and metastatic potential in experimental colon cancer

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Zinc deficiency teratogenicity: the protective role of maternal tissue catabolism

For this FY 2024 proposed rule, to comply with the requirement that MS-DRG reclassification and recalibration of the relative weights be budget neutral for the standardized amount and the hospital-specific rates, we used FY 2022 discharge data to simulate payments and compared the following: Aggregate payments using the FY 2023 labor-related share percentages, the FY 2023 relative weights, and the FY 2023 pre-reclassified wage data, and applied the proposed proxy FY 2024 hospital readmissions payment adjustments and proposed proxy FY 2024 hospital VBP payment adjustments

While our findings provided initial evidence suggesting the involvement of MAPK signaling, additional investigations, such as gain- or loss-of-function studies, are needed to confirm this relationship and further elucidate the underlying mechanisms