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Nonetheless, the utilization of HO-1 target in the treatment of diabetic nephropathy is still in the examination stage and requires further clinical trials for its efficacy and safety

Other research confirms that both homozygous C677T (T677T) and compound heterozygous (C677T + A1298C) are linked with higher homocysteine concentrations and greater risk of heart disease (10)

The latter process again involves a specific electroneutral, carrier-mediated mechanism (25)

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