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10.3390/antiox7050062 16 GoutelleS.BourguignonL.MaireP

10.3892/br.2025.1944 Biomed

B12 Deficiency Awareness: Recognise signs and symptoms of deficiency, and understand how supplementation can help

2015;6 doi: 10.1038/ncomms10112

These modifications collectively address the major limitations of natural amylin - its tendency to aggregate into toxic fibrils, rapid degradation, and poor pharmacokinetic properties - while preserving and enhancing its beneficial metabolic effects