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Hagihara, Y

Aging 11(14):51405157

Ok CY, Salim AA, Loghavi S, Rajyalakshmi L, Routbort MJ, Singh RR, Zuo Z, Pierce S, Garcia-Manero G, Kantarjian HM, Cortes JE, Ravandi F, Andreeff M , Medeiros LJ, Patel KP

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In the presence of small molecules that scavenge lipid dicarbonyls, the ability of MPO to crosslink ApoAI is markedly reduced (283)

Drug targets are typically macromolecules, such as proteins or nucleic acids, that interact specifically with therapeutic compounds, mediating pharmacological effects or enabling targeted delivery