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GSH constrains NLRP3 activation primarily by scavenging H 2 O 2 and preserving mitochondrial redox balance

If the goal is to qualitatively profile changes in cellular protein sulfenylation, this level of reactivity and trapping is sufficient, given the high sensitivity afforded by subsequent chemiluminescent and fluorescent signals

Desipramine induces eryptosis in human erythrocytes, an effect blunted by nitric oxide donor sodium nitroprusside and N-acetyl-L-cysteine but enhanced by calcium depletion

The TH production, per se , is a high source of ROS in the thyrocyte

I., Miklasz, S