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However, evidence from sub-Saharan Africa suggests wide variability in the use of herbal medicines during pregnancy ( Figure 2 ), from 2.0% as reported in a study conducted in the Tigray Region, Northern Ethiopia (Gebremedhin and Gomathi, 2014) to 100% according to another study in Machakos District, Eastern Kenya (Kaingu et al., 2011)

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Liquid KD formulas with the classic 4:1 ketogenic ratio (4 g of fat per 1 g of protein and carbohydrates combined) are also available (257)

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A tailored, integrated, patient-centred treatment is essential to optimize pain management in constipation